|
KMID : 0614019890050010023
|
|
Journal of Pharmaceutical Sciences (C.N.U.)
1989 Volume.5 No. 1 p.23 ~ p.29
|
|
|
The Study on the Antibacterial Components of Higher Plants Against A Cariogenic Bacterium, Streptococcus Mutans
|
|
Bae Ki-Hwan
|
|
|
Abstract
|
|
|
|
The methanol extracts of Magnolia obovata, Liriodendron tulipifera, Reynoutria elliptica, and Commelina communis showed strong inhibiting activity on the growth of Streptococcus mutans OMZ 176 which has been known as a main cariogenic becterium. The fractionaion of the extracts, monitored with the bioassay, resulted in the isolation of the active components. Magnolol and honokiol were isolated from M. obovata, β-liriodenolide from L. tulipifera, emodin from R. elliptica, harman and norharman from C. communis. The chemical structure and activity relationships of the lignans (magnolol and honokiol) and β-carboline alkaloids (harman and norharman) are also discussed.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|